Santa Clara vs. Louisiana betting: College basketball preview for Nov. 21

Data Skrive
Data Skrive

The Louisiana Ragin’ Cajuns (1-4) are heavy underdogs (by 19.5 points) to end a three-game road losing streak when they visit the Santa Clara Broncos (5-0) on Friday, November 21, 2025 at 10 p.m. ET. The matchup has an over/under of 139.5 points.

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Spread

Santa Clara Cover -19.5 vs Louisiana -109

Bet $20, Payout $38.35

Santa Clara vs. Louisiana betting lines

  • Santa Clara moneyline odds to win: -3846
  • Louisiana moneyline odds to win: +1413
  • Spread: Santa Clara (-19.5)
  • Total: 139.5

Santa Clara statistics, trends and more

As the home team

  • Against the spread last year, Santa Clara fared worse at home, covering seven times in 15 home games, and seven times in 11 road games.
  • In terms of point totals, the Broncos hit the over less often when playing at home last season, as they exceeded the total seven times in 15 opportunities (46.7%). In road games, they hit the over six times in 11 opportunities (54.5%).
  • As a moneyline favorite last year, Santa Clara won 11 of 13 games at home, good for a .846 winning percentage. Santa Clara won four of five games away from home (.800) as a moneyline favorite.

Last season stats

  • Offensively, the Broncos were the 21st-best team in the country (81.9 points per game) last season. On defense, they were 209th (73.0 points allowed per game).
  • Last season, Santa Clara was 43rd in college basketball in rebounds (34.7 per game) and 99th in rebounds conceded (30.0).
  • The Broncos were eighth-best in college basketball in assists (17.3 per game) last year.

Santa Clara betting records this season

  • ATS Record: 3-1-0 (Home: 2-1-0; Away: 1-0-0)
  • O-U-P: 2-2-0 (Home: 1-2-0; Away: 1-0-0)
  • Record When Moneyline Favorite: 3-0 (Home: 3-0; Away: 0-0)
  • Record When Moneyline Underdog: 1-0 (Home: 0-0; Away: 1-0)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
47.4 (111th in nation) 38.8 (64th) 38.6 (60th) 28.0 (66th) 19.4 (28th) 10.6 (95th)

Need to know more about sports betting before you put down a wager on Santa Clara vs. Louisiana? Here’s everything you need to know about how to bet.

Louisiana statistics, trends and more

As the away team

  • Against the spread last season, Louisiana had better results away (7-4-0) than at home (5-11-0).
  • In 2024-25, a lower percentage of the Ragin’ Cajuns’ games finished above the over/under at home (25%, four of 16) compared to away (36.4%, four of 11).
  • When moneyline underdogs last season, the Ragin’ Cajuns won a lower percentage of games at home (2-8) than away (4-5).

Last season stats

  • The Ragin’ Cajuns struggled to score points last year, ranking eighth-worst in college basketball with 65.4 points per game. They did better defensively, ranking 209th by allowing 73.0 points per contest.
  • It was a tough season for Louisiana last year in terms of rebounding, as it grabbed just 27.1 rebounds per game (sixth-worst in college basketball) and allowed 34.9 rebounds per contest (12th-worst).
  • The Ragin’ Cajuns didn’t produce many assists last season, ranking second-worst in the nation with 10.3 assists per contest.

Louisiana betting records this season

  • ATS Record: 2-3-0 (Home: 2-0-0; Away: 0-3-0)
  • ATS Record When Underdog by 19.5+: 0-1-0 (As Favorite: 1-0-0; As Underdog: 1-3-0)
  • O-U-P: 2-3-0 (Home: 0-2-0; Away: 2-1-0)
  • Record When Moneyline Favorite: 1-0 (Home: 1-0; Away: 0-0)
  • Record When Moneyline Underdog: 0-4 (Home: 0-1; Away: 0-3)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
42.2 (297th in nation) 46.6 (300th) 26.8 (346th) 30.0 (130th) 8.0 (362nd) 10.8 (103rd)
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