Santa Clara vs. San Francisco betting: College basketball preview for Feb. 21

Data Skrive
Data Skrive

The San Francisco Dons (15-14, 7-9 WCC) are 7-point underdogs as they try to stop a three-game home losing streak when they take on the Santa Clara Broncos (22-6, 13-2 WCC) on Saturday, February 21, 2026 at War Memorial at the Sobrato Center. The contest airs at 10 p.m. ET on CBS Sports Network. The matchup has an over/under of 159.5.

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Spread

Santa Clara Cover -7 vs San Francisco -113

Bet $20, Payout $37.70

Santa Clara vs. San Francisco betting lines

  • Santa Clara moneyline odds to win: -337
  • San Francisco moneyline odds to win: +261
  • Spread: Santa Clara (-7)
  • Total: 159.5

Santa Clara statistics, trends and more

As the away team

  • Santa Clara has done a better job covering the spread at home (8-5-0) than it has in road affairs (5-4-0).
  • The Broncos have gone over the total less often when playing at home, hitting the over in eight of 13 home matchups (61.5%). In away games, they have hit the over in seven of nine games (77.8%).
  • As a moneyline favorite, Santa Clara has taken 12 of 12 games when playing at home, good for a 1.000 winning percentage. It has won six of seven games away from home (.857) as a moneyline favorite.

Recent trends

  • The Broncos have seen an uptick in scoring lately, putting up 86.4 points per game in their last 10 contests, 2.7 points more than the 83.7 they’ve scored this season.
  • The past 10 games have seen Santa Clara concede 0.9 more points per game (72.8) than its season-long average (71.9).
  • The Broncos are trending up from deep during their last 10 outings, making 9.9 threes per game and shooting 37.1% from long range in comparison to their season-long averages of 9.8 makes and 34.0% from distance in the 2025-26 season.

Santa Clara betting records this season

  • ATS Record: 15-12-0 (Home: 8-5-0; Away: 5-4-0)
  • ATS Record When Favored by 7+: 6-9-0 (As Favorite: 12-11-0; As Underdog: 3-1-0)
  • O-U-P: 18-9-0 (Home: 8-5-0; Away: 7-2-0)
  • Record When Moneyline Favorite: 20-3 (Home: 12-0; Away: 6-1)
  • Record When Moneyline Underdog: 1-3 (Home: 0-1; Away: 1-1)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
47.4 (56th in nation) 44.9 (230th) 33.0 (124th) 29.7 (97th) 17.1 (33rd) 10.7 (145th)

Need to know more about sports betting before you put down a wager on Santa Clara vs. San Francisco? Here’s everything you need to know about how to bet.

San Francisco statistics, trends and more

As the home team

  • In 2025-26 against the spread, San Francisco has a lower winning percentage at home (.308, 4-9-0 record) than away (.500, 5-5-0).
  • Looking at the over/under, Dons games have finished over more often at home (seven of 13, 53.8%) than away (five of 10, 50%).
  • When moneyline underdogs, the Dons have won a lower percentage of games at home (0-2) than on the road (1-6).

Recent trends

  • The Dons are averaging 72.2 points per contest in their past 10 games, which is 2.3 fewer points than their average for the season (74.5).
  • San Francisco is ceding 81.2 points per contest in its last 10 games, which is 8.2 more points than it is allowing for the season (73.0).
  • In their past 10 games, the Dons are sinking 8.3 threes per contest, 0.6 fewer threes than their season average (8.9). They have a higher three-point percentage over their past 10 games (34.9%) compared to their season average (34.3%).

San Francisco betting records this season

  • ATS Record: 12-16-0 (Home: 4-9-0; Away: 5-5-0)
  • ATS Record When Underdog by 7+: 2-3-0 (As Favorite: 7-10-0; As Underdog: 5-6-0)
  • O-U-P: 15-13-0 (Home: 7-6-0; Away: 5-5-0)
  • Record When Moneyline Favorite: 11-6 (Home: 8-3; Away: 2-1)
  • Record When Moneyline Underdog: 3-8 (Home: 0-2; Away: 1-6)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
43.5 (281st in nation) 44.2 (184th) 33.4 (106th) 28.6 (45th) 13.9 (175th) 10.7 (145th)
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