Mariners vs. Astros Betting Lines, Odds, & Player Matchups May 22, 2025

Data Skrive
Data Skrive

The Seattle Mariners (27-20) visit the Houston Astros (25-23) on Thursday to begin a four-game series, with the first pitch at 8:10 p.m. ET from Daikin Park. The favored Mariners (-131) head into the matchup following a series split with the White Sox, and the underdog Astros (+112) are coming off of a series split with the Rays. Seattle’s George Kirby and Houston’s Lance McCullers will take the mound first.

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Odds to Win

Mariners to win vs Astros -131

Bet $20, Payout $35.27

Mariners vs. Astros betting lines

  • Favorite: Mariners (-131)
  • Underdog: Astros (+112)
  • Over/under: 8

Mariners betting info, hitting leaders, & pitching

Mariners betting info

  • The Mariners have been favored on the moneyline 28 total times this season. They’ve gone 16-12 in those games.
  • In games it has played as moneyline favorites with odds of -131 or shorter, Seattle has a 12-8 record (winning 60% of its games).
  • The implied moneyline probablility for this matchup gives the Mariners a 56.7% chance to win.
  • Seattle has had an over/under set by oddsmakers 47 times, and have combined with opponents to go over the total in 25 of those games (25-20-2).
  • The Mariners have covered 51.1% of their games this season, going 24-23-0 ATS.

Mariners hitting info

  • Cal Raleigh paces the Mariners with 15 home runs and 32 runs batted in.
  • In MLB action, Raleigh ranks fourth in home runs and 19th in RBI.
  • Julio Rodriguez has five doubles, two triples, eight home runs and 18 walks while batting .232.
  • Among all MLB batters, Rodriguez ranks 41st in homers and 58th in RBI.
  • Jorge Polanco has six doubles, 10 home runs and eight walks while hitting .306.
  • J.P. Crawford has a club-best .274 batting average.
  • Crawford heads into this game on a three-game hitting streak. In his last five games he is batting .294 with a double, a home run, six walks and an RBI.

Mariners pitching rankings

  • The Mariners pitching staff ranks 18th in the majors with a collective 8.2 strikeouts per nine innings.
  • Seattle has the 12th-ranked team ERA among all MLB pitching staffs (3.73).
  • The Mariners average MLB’s 19th-ranked WHIP (1.305).
  • Mariners pitchers combine to give up the 10th-fewest home runs in baseball (44 total, 0.9 per game).
  • Seattle struck out eight White Sox batters while giving up seven hits in a 1-0 loss in its last game.

Astros betting info, hitting leaders, & pitching

Astros betting info

  • The Astros have entered the game as underdogs 16 times this season and won seven, or 43.8%, of those games.
  • This season, Houston has won three of its seven games when it’s the underdog by at least +112 on the moneyline.
  • The implied probability of a win by the Astros, based on the moneyline, is 47.2%.
  • So far this season, Houston and its opponents have hit the over in 19 of its 48 games with a total.
  • The Astros are 26-22-0 against the spread this season.

Astros hitting info

  • Isaac Paredes leads Houston in home runs (eight) and runs batted in (25) this season while batting .264.
  • Among all batters in the big leagues, Paredes ranks 41st in home runs and 58th in RBI.
  • Paredes has hit safely in five games in a row. During his last five outings he is hitting .300 with two home runs, two walks and six RBIs.
  • Jeremy Pena has collected 55 hits this season and has an OBP of .358. He’s slugging .445 on the year.
  • Pena is 81st among hitters in the majors in homers, and 74th in RBI.
  • Jake Meyers is batting .307 to lead Houston, while adding three homers and 16 runs batted in this season.
  • Meyers brings a five-game hitting streak into this game. During his last five outings he is hitting .412 with a double, a home run, three walks and two RBIs.
  • Jose Altuve has 44 hits and an OBP of .294 to go with a slugging percentage of .341 this season.

Astros pitching rankings

  • The Astros have a 9.4 K/9 this season as a pitching staff, third-best in baseball.
  • Houston pitchers have a combined ERA of 3.38 ERA this year, sixth-best in baseball.
  • The Astros have a combined 1.123 WHIP as a pitching staff, which is the best in baseball this season.
  • With just 42 homers allowed, the Astros rank seventh in the league at preventing long balls.
  • Houston pitchers struck out five Rays hitters while allowing six base hits in a 3-2 loss its last time out.
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