The South Carolina Gamecocks (2-2) host an SEC battle against the Kentucky Wildcats (2-1) on Saturday, September 27, 2025 at Williams-Brice Stadium.

The Gamecocks are the favorites (-5.5) in their matchup against the Wildcats, with the over/under being 47.5 points. (In terms of the moneyline, the Gamecocks are -221 and the Wildcats are +181.)

Below you’ll find our betting primer for this this matchup between the Gamecocks and the Wildcats, and uncover all of our predictions here, too!

South Carolina vs. Kentucky betting lines

• Spread favorite: Gamecocks (-5.5)
• Moneyline: Gamecocks (-221), Wildcats (+181)
• Total: 47.5 points
• TV Channel: SEC Network
• Live Stream: Fubo

South Carolina vs. Kentucky betting info and stats

South Carolina has won twice against the spread so far this season (2-2-0). South Carolina has covered the spread once when the favorite by at least 5.5 points (a 1-1 ATS record). South Carolina split the two games it has played as the moneyline favorite this season. Kentucky, through three games with a set spread so far this season, is 1-2-0 against the spread. When Kentucky is an underdog by 5.5 points or more, it has posted a record of 1-0 ATS. Kentucky has played as the underdog on the moneyline one time this season, and failed to pick up the victory.

South Carolina vs. Kentucky key players

South Carolina Gamecocks

• LaNorris Sellers has recorded 733 yards (183.3 ypg) on 47-of-73 passing with four touchdowns compared to one interception this season.
• Rahsul Faison has racked up 140 yards on 33 carries while finding the end zone one time as a runner.
• Oscar Adaway III has piled up 93 yards on 25 attempts, scoring one time.
• Vandrevius Jacobs’ leads his squad with 215 yards as a receiver. He’s racked up that yardage on 13 receptions (out of 15 targets) and scored two touchdowns.
• Nyck Harbor has caught 10 passes for 210 yards (52.5 yards per game) and one touchdown this year.
• Donovan Murphree has a total of 94 receiving yards so far this year, hauling in five throws.
• Dylan Stewart paces the team with 3.0 sacks, and also has 5.0 TFL and 18 tackles.
• Jalon Kilgore, South Carolina’s tackle leader, has 18 tackles this year.
• Justin Okoronkwo leads the team with one interception, while also collecting 16 tackles, 1.0 TFL, and one pass defended.

Kentucky Wildcats

• Cutter Boley has recored 278 passing yards, or 139.0 per game, so far this season. He has completed 54.2% of his passes and has tossed two touchdowns with zero interceptions. He’s also contributed on the ground with 19.0 rushing yards per game.
• Seth McGowan has run the ball 51 times for 275 yards, with six touchdowns.
• Dante Dowdell has piled up 214 yards (on 36 attempts) with one touchdown.
• Josh Kattus leads his squad with 112 receiving yards on eight receptions with one touchdown.
• Jay Maclin has collected 103 receiving yards (34.3 yards per game) on four receptions.
• Hardley Gilmore IV has racked up 97 reciving yards (32.3 ypg) this season.
• Steven Soles Jr. has 2.0 sacks to pace the team, and also has six tackles.
• Alex Afari is the team’s leading tackler this year. He’s amassed 26 tackles, 3.0 TFL, and one sack.
• Ty Bryant leads the team with two interceptions, while also collecting 21 tackles and two passes defended.