The Indiana State Sycamores (10-19, 3-15 MVC) are underdogs (+8.5) as they attempt to end a five-game losing streak when they visit the Southern Illinois Salukis (14-15, 8-10 MVC) at 8 p.m. ET on Wednesday, February 25, 2026 at Banterra Center. The matchup airs on ESPN+. The point total for the matchup is set at 147.5.

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Southern Illinois vs. Indiana State betting lines

• Southern Illinois moneyline odds to win: -402
• Indiana State moneyline odds to win: +306
• Spread: Southern Illinois (-8.5)
• Total: 147.5

Southern Illinois statistics, trends and more

As the home team

• Southern Illinois owns a worse record against the spread at home (4-8-0) than it does in away games (9-5-0).
• The Salukis have exceeded the total in four of 12 home games (33.3%), compared to four of 14 road games (28.6%).
• Southern Illinois has won a lower percentage of its matchups as a moneyline favorite at home, going 5-4 (.556). On the road as a moneyline favorite, it sports a record of 2-1 (.667).

Recent trends

• The Salukis have seen a decrease in scoring lately, racking up 68.0 points per game in their last 10 contests, 5.3 points fewer than the 73.3 they’ve scored this season.
• Southern Illinois has been tougher on the defensive side of the ball lately, allowing 64.1 points per game over its past 10 contests compared to the 70.2 points per game its opponents are averaging on the 2025-26 season.
• The Salukis’ last 10 outings have seen them make 5.1 three-pointers per game while shooting 29.1% from beyond the arc. Both numbers are up compared to their 2025-26 averages of 5.0 makes and 28.4%.

Southern Illinois betting records this season

• ATS Record: 14-14-0 (Home: 4-8-0; Away: 9-5-0)
• ATS Record When Favored by 8.5+: 3-1-0 (As Favorite: 6-7-0; As Underdog: 8-7-0)
• O-U-P: 8-20-0 (Home: 4-8-0; Away: 4-10-0)
• Record When Moneyline Favorite: 8-5 (Home: 5-4; Away: 2-1)
• Record When Moneyline Underdog: 5-10 (Home: 1-2; Away: 4-7)

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Indiana State statistics, trends and more

As the away team

• Indiana State has been better against the spread on the road (11-3-0) than at home (6-6-0) this year.
• Sycamores games have finished above the over/under less often at home (five times out of 12) than away (seven of 14) this year.
• The Sycamores’ winning percentage at home when moneyline underdogs is .333 (2-4), and away it is .154 (2-11).

Recent trends

• The Sycamores have fared worse offensively over their last 10 games, averaging 70.2 points per contest, 4.2 fewer points their than season average of 74.4.
• Indiana State is surrendering 76.4 points per game over its last 10 games, compared to its season average of 75.6 points allowed.
• The Sycamores are draining 7.9 threes per game over their previous 10 games, which is 0.3 fewer three-pointers than their average for the season (8.2). That said, they sport a higher three-point percentage over their past 10 contests (32.4%) compared to their season average from three-point land (31.6%).

Indiana State betting records this season

• ATS Record: 17-10-0 (Home: 6-6-0; Away: 11-3-0)
• ATS Record When Underdog by 8.5+: 4-2-0 (As Favorite: 4-4-0; As Underdog: 13-6-0)
• O-U-P: 13-14-0 (Home: 5-7-0; Away: 7-7-0)
• Record When Moneyline Favorite: 4-4 (Home: 3-3; Away: 1-0)
• Record When Moneyline Underdog: 4-15 (Home: 2-4; Away: 2-11)