Cardinals vs. White Sox Betting Lines, Odds, & Player Matchups June 18, 2025

Data Skrive
Data Skrive

Brendan Donovan leads the St. Louis Cardinals (38-35) into a matchup with the Chicago White Sox (23-50) following his four-hit showing in a 12-2 win over the White Sox. The Cardinals are favored (-191) for this game against the underdog White Sox (+158), which begins at 7:40 p.m. ET on Wednesday. St. Louis has Sonny Gray starting things off, while Chicago will counter with Sean Burke.

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Betting Odds

Cardinals to win vs White Sox -191

Bet $20, Payout $30.47

Cardinals vs. White Sox betting lines

  • Favorite: Cardinals (-191)
  • Underdog: White Sox (+158)
  • Over/under: 8.5

Cardinals betting info, hitting leaders, & pitching

Cardinals betting info

  • The Cardinals have won 50% of the games this season when they were the moneyline favorite (16-16).
  • St. Louis has not played a game this season with moneyline odds of -191 or shorter.
  • The implied moneyline probablility in this matchup gives the Cardinals a 65.6% chance to win.
  • St. Louis has played in 73 games with a set over/under, and have combined with its opponents to go over the total 39 times (39-32-2).
  • The Cardinals have a 41-32-0 record ATS this season (covering 56.2% of the time).

Cardinals hitting info

  • Donovan has a team-best batting average of .323.
  • Donovan ranks 207th in home runs and 120th in RBI among all hitters in baseball.
  • Donovan has hit safely in two games in a row. During his last five outings he is batting .409 with two doubles and an RBI.
  • Nolan Arenado is hitting .244 with 11 doubles, a triple, eight home runs and 22 walks.
  • Arenado ranks 102nd in home runs and 62nd in RBI this year.
  • Arenado takes a seven-game hitting streak into this game. During his last 10 outings he is hitting .286 with a double, a home run, two walks and five RBIs.
  • Willson Contreras paces the Cardinals in home runs (nine) and runs batted in (45).
  • Lars Nootbaar has 12 doubles, eight home runs and 40 walks while hitting .223.

Cardinals pitching rankings

  • The pitching staff for the Cardinals has a collective 7.3 K/9, the second-worst in the majors.
  • St. Louis has the 19th-ranked team ERA among all MLB pitching staffs (3.97).
  • The Cardinals average baseball’s 16th-ranked WHIP (1.274).
  • Cardinals pitchers combine to surrender 59 home runs (0.8 per game), the third-fewest in baseball.
  • St. Louis struck out five White Sox batters while allowing six hits in a 12-2 win in its last game.

White Sox betting info, hitting leaders, & pitching

White Sox betting info

  • The White Sox have won 23, or 31.5%, of the 73 games they’ve played as underdogs this season.
  • Chicago is 9-30 this season when entering a game as the underdog by +158 or more on the moneyline.
  • Sportsbooks have implied with the moneyline set for this matchup that the White Sox have a 38.8% chance to win.
  • So far this season, Chicago and its opponents have hit the over in 33 of its 73 games with a total.
  • The White Sox are 42-31-0 against the spread this season.

White Sox hitting info

  • Miguel Vargas leads Chicago in batting average (.242), home runs (10) and runs batted in (31) this season.
  • Among all batters in MLB, Vargas is 61st in home runs and 91st in RBI.
  • Vargas has hit safely in six straight games. In his last 10 outings he is hitting .270 with four doubles, a triple, two home runs, five walks and five RBIs.
  • Chase Meidroth is batting .276 with an OBP of .358 and a slugging percentage of .337 this season.
  • Meidroth is 269th in home runs and 309th in RBI among all hitters in the major leagues.
  • Andrew Benintendi has collected 38 base hits, an OBP of .302 and a slugging percentage of .414 this season.
  • Luis Robert has collected 43 hits this season and has an OBP of .275. He’s slugging .305 on the year.

White Sox pitching rankings

  • The White Sox strike out just 7.5 batters per nine innings as a pitching staff, which ranks 27th in MLB.
  • Chicago has the 23rd-ranked ERA (4.24) in the majors this season.
  • The White Sox rank 25th in MLB with a combined 1.409 WHIP this season.
  • With 77 homers allowed, the White Sox rank 16th in the league at preventing long balls.
  • Chicago pitchers struck out five Cardinals hitters while allowing 13 base hits in a 12-2 loss its last time out.
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