The Syracuse Orange (1-1) take on an FCS opponent, the Colgate Raiders (0-2), on Friday, September 12, 2025 at the JMA Wireless Dome.

The Orange are expected to win by at least two TDs (currently -37.5) versus the Raiders. The over/under for this matchup is 66.5 points.

Below you can find our betting primer for this this game between the Orange and the Raiders, and uncover all of our betting picks here, too!

Syracuse vs. Colgate betting lines

• Spread favorite: Orange (-37.5)
• Moneyline: Orange (), Raiders ()
• Total: 66.5 points
• TV Channel: ACC Network
• Live Stream: Fubo

Syracuse vs. Colgate betting info and stats

Syracuse has not won a game against the spread so far this season (0-1-1). In one game as the moneyline favorite, Syracuse won. Colgate, through two games with a spread so far this season, is unbeaten (2-0-0) against the spread. Colgate has been the underdog on the moneyline two times this season, and it lost both games.

Syracuse vs. Colgate key players

Syracuse Orange

• Steve Angeli has thrown for 691 yards (345.5 ypg) to lead Syracuse, completing 60.2% of his passes and collecting three touchdown passes compared to two interceptions this season.
• Yasin Willis has 139 rushing yards on 34 carries with four touchdowns.
• Will Nixon has been handed the ball 18 times this year and racked up 63 yards (31.5 per game). He’s also contributed in the pass game with eight grabs for 76 yards
• Dan Villari’s team-high 159 yards as a receiver have come on 12 catches (out of 16 targets).
• Justus Ross-Simmons has grabbed eight passes while averaging 66.5 yards per game and scoring two touchdowns.
• Darrell Gill Jr. has compiled six grabs for 117 yards, an average of 58.5 yards per game.
• Kevin Jobity Jr. has racked up 1.0 sack to pace the team, while also recording 2.0 TFL and four tackles.
• Darian Chestnut, Syracuse’s leading tackler, has 18 tackles this year.

Colgate Raiders

• Zach Osborne has been a dual threat for Colgate this season. He has 466 passing yards (233.0 per game) while completing 59.1% of his passes. He’s tossed four touchdown passes and zero interceptions this season. On the ground, he’s compiled 80 yards (40.0 ypg) on 16 carries.
• Brendan Cassamajor has run for 61 yards across 18 attempts.
• Treyvhon Saunders has racked up 360 receiving yards on 23 receptions to pace his squad so far this season while scoring three touchdowns as a receiver.
• Winston Moore has four receptions (on four targets) for a total of 98 yards (49.0 yards per game) and one touchdown this year.
• Reed Swanson’s three targets have resulted in three catches for 57 yards.
• Daniel Shaban has sacks to pace the team, and also has 18 tackles.
• Colgate’s tackle leader, Brady Hutchison, has 18 tackles this year.
• Tymir Wynn leads the team with two interceptions, while also putting up 18 tackles.