Nationals vs. White Sox Betting Lines, Odds, & Player Matchups September 26, 2025

Data Skrive
Data Skrive

James Wood leads the Washington Nationals (65-94) into a contest against the Chicago White Sox (58-101) after his two-home run performance in a 4-3 win over the Braves. The Nationals are favored on the moneyline (-131) in this game against the underdog White Sox (+110), which starts at 6:45 p.m. ET on Friday. Washington has Cade Cavalli set to start, and Chicago will counter with Yoendrys Gomez.

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Moneyline

Nationals to win vs White Sox -131

Bet $20, Payout $35.27

Nationals vs. White Sox betting lines

  • Favorite: Nationals (-131)
  • Underdog: White Sox (+110)
  • Over/under: 8.5

Nationals betting info, hitting leaders, & pitching

Nationals betting info

  • The Nationals have been the moneyline favorite 18 total times this season. They’ve gone 6-12 in those games.
  • When it has played as moneyline favorites with odds of -131 or shorter, Washington has a 2-7 record (winning just 22.2% of its games).
  • The Nationals have an implied moneyline win probability of 56.7% in this matchup.
  • Washington has combined with opponents to hit the over on the total 78 times this season for a 78-71-9 record against the over/under.
  • The Nationals have gone 78-80-0 ATS this season.

Nationals hitting info

  • C.J. Abrams has racked up a team-high batting average of .259.
  • Abrams’ home runs rank 103rd in MLB and he ranks 130th in RBI in MLB.
  • Abrams has safely hit in two games in a row. During his last five outings he is hitting .182 with two doubles, a home run and four RBIs.
  • Wood has hit 30 home runs with 92 runs batted in. Both lead his team.
  • Wood ranks 25th in home runs and 25th in RBI among MLB hitters this season.
  • Wood takes a three-game hitting streak into this matchup. In his last five games he is hitting .278 with a double, three home runs, three walks and three RBIs.
  • Luis Garcia is batting .251 with 28 doubles, a triple, 13 home runs and 26 walks.
  • Josh Bell is hitting .235 with 15 doubles, a triple, 21 home runs and 56 walks.

Nationals pitching rankings

  • The Nationals pitching staff is 26th in the majors with a collective 7.9 strikeouts per nine innings.
  • Washington has the 29th-ranked team ERA among all MLB pitching staffs (5.34).
  • The Nationals have the second-highest WHIP in the majors (1.447).
  • Nationals pitchers combine to give up the fifth-most home runs in baseball (207 total, 1.3 per game).
  • Washington defeated the Braves 4-3 in its last game with 11 strikeouts while allowing six hits.

White Sox betting info, hitting leaders, & pitching

White Sox betting info

  • The White Sox have won 57, or 36.5%, of the 156 games they’ve played as underdogs this season.
  • Chicago is 51-89 this season when entering a game as the underdog by +110 or more on the moneyline.
  • The implied probability of a win by the White Sox, based on the moneyline, is 47.6%.
  • Chicago and its opponents have gone over the total this season in 71 of its 159 opportunities.
  • The White Sox are 92-67-0 against the spread in their 159 chances this season.

White Sox hitting info

  • Miguel Vargas has been key for Chicago with 114 hits, an OBP of .314 plus a slugging percentage of .396.
  • Vargas’ home run total ranks 138th in the big leagues, and he is 135th in RBI.
  • Vargas has safely hit in six games in a row. In his last 10 outings he is batting .265 with two doubles, a home run, four walks and five RBIs.
  • Lenyn Sosa leads Chicago in batting average (.259), home runs (21) and runs batted in (72) this season.
  • Sosa currently ranks 68th in homers and 77th in RBI in the big leagues.
  • Sosa has hit safely in two games in a row. During his last five outings he is hitting .167 with a home run and two RBIs.
  • Chase Meidroth is slashing .257/.335/.326 this season for the White Sox.
  • Colson Montgomery is batting .231 with an OBP of .305 and a slugging percentage of .508 this season.
  • Montgomery has hit safely in seven straight games. During his last 10 outings he is hitting .278 with two doubles, a home run, six walks and two RBIs.

White Sox pitching rankings

  • The White Sox strike out 8.1 batters per nine innings as a pitching staff, 22nd in MLB.
  • Chicago has pitched to a 4.26 ERA this season, which ranks 21st in baseball.
  • The White Sox have a combined 1.373 WHIP as a pitching staff, fourth-highest in MLB.
  • The White Sox have allowed the 14th-fewest home runs this season with 180, or 1.1 per game.
  • Chicago suffered a 5-3 defeat in its most recent game, as its pitchers struck out eight Yankees batters while allowing eight hits.
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