MWC opponents meet when the Wyoming Cowboys (3-4) and the Colorado State Rams (2-5) square off on Saturday, October 25, 2025 at Jonah Field at War Memorial Stadium.

The Cowboys are the favorites (-4.5) in their game against the Rams, with the over/under being 46.5 points. (On the moneyline, the Cowboys are -203 and the Rams are +169.)

Below you can find our preview for this this game between the Cowboys and the Rams, and discover all of our expert picks here, too!

Wyoming vs. Colorado State betting lines

• Spread favorite: Cowboys (-4.5)
• Moneyline: Cowboys (-203), Rams (+169)
• Total: 46.5 points
• TV Channel: CBS Sports Network
• Live Stream: Fubo

Wyoming vs. Colorado State betting info and stats

Wyoming has four wins against the spread through seven opportunities so far this season (4-3-0). Wyoming is undefeated ATS (2-0) when favored by at least 4.5 points. Wyoming has won both games as a moneyline favorite this season. Colorado State has three wins against the spread so far this season (3-4-0). Colorado State has covered the spread three times (3-1) in the four games it has been the underdog by at least 4.5 points. Colorado State has a 1-3 record this year in games it hs played as an underdog on the moneyline.

Wyoming vs. Colorado State recent stats and trends

Wyoming Cowboys

• Wyoming is 2-1 against the spread and 1-2 overall during its past three matchups.
• In one of those three games, the final combined score surpassed the set total.
• The past three Wyoming games averaged 5.8 more points (52.3) than this matchup’s over/under.

Colorado State Rams

• Colorado State has covered the spread once in its last three contests while putting together a 1-2 record straight-up in those games.
• The final combined score of the past three Colorado State games has exceeded the set total twice.
• Colorado State’s last three games have ended with an average of 47.2 points scored. That’s 0.7 more points than this contest’s over/under.

Wyoming vs. Colorado State key players

Wyoming Cowboys

• Kaden Anderson has 1,480 passing yards for Wyoming, completing 58.8% of his passes and tossing nine touchdowns and six interceptions this season.
• The team’s top rusher, Samuel Harris, has carried the ball 69 times for 398 yards (56.9 per game) and one touchdown. He’s proven to be a dual threat, hauling in 158 receiving yards on 13 catches.
• Sam Scott has carried the ball 65 times for 278 yards (39.7 per game) and one touchdown.
• Chris Durr Jr.’s team-high 375 yards as a receiver have come on 31 receptions (out of 42 targets) with three touchdowns.
• Jaylen Sargent has hauled in 15 receptions totaling 192 yards so far this campaign.
• Ben Florentine paces the team with 4.0 sacks, and also has 4.0 TFL and 13 tackles.
• Evan Eller is the team’s tackle leader this year. He’s racked up 33 tackles, 2.0 TFL, one sack, and one interception.
• Brayden Johnson has a team-high two interceptions to go along with 31 tackles, 2.0 TFL, one sack, and two passes defended.

Colorado State Rams

• Jackson Brousseau leads Colorado State with 741 yards on 69-of-112 passing with six touchdowns compared to zero interceptions this season.
• Jalen Dupree has run for 429 yards on 83 carries so far this year while scoring two times on the ground.
• Lloyd Avant has compiled 328 yards on 57 carries with three touchdowns.
• Armani Winfield has racked up 261 receiving yards on 19 receptions to pace his team so far this season while scoring two touchdowns as a receiver.
• Tommy Maher has put up a 176-yard season so far. He’s caught 16 passes on 28 targets.
• Keyonta Lanier’s 10 grabs (on 16 targets) have netted him 113 yards (16.1 ypg).
• Lemondre Joe has collected 2.5 sacks to lead the team, while also picking up 3.0 TFL, 26 tackles, and one interception.
• Owen Long, Colorado State’s tackle leader, has 76 tackles, 2.0 TFL, and one sack this year.
• Jace Bellah has picked off a team-leading three passes. He also has 11 tackles and three passes defended to his name.