The Clemson Tigers (2-3) square off against a conference opponent when they visit the Boston College Eagles (1-4) on Saturday, October 11, 2025 at Alumni Stadium (Chestnut Hill, MA) in an ACC showdown.

The Tigers are very big favorites (currently -14) in their game versus the Eagles, with the over/under at 54.5 points. (In terms of the moneyline, the Tigers are -592 and the Eagles are +434.)

Below you can find our preview for this this game between the Tigers and the Eagles, and uncover all of our predictions here, too!

Clemson vs. Boston College betting lines

• Spread favorite: Tigers (-14)
• Moneyline: Tigers (-592), Eagles (+434)
• Total: 54.5 points
• TV Channel: ACC Network
• Live Stream: Fubo

Clemson vs. Boston College betting info and stats

Clemson has one win against the spread this season (1-4-0). Clemson has covered the spread once when the favorite by at least 14 points (a 1-2 ATS record). In five games as the moneyline favorite, Clemson has gone 2-3. Boston College, through five games with a set spread this season, is 2-3-0 against the spread. This is the third game this year Boston College is an underdog on the moneyline, after losing the previous two such games.

Clemson vs. Boston College recent stats and trends

Clemson Tigers

• Clemson has covered the spread once in its past three contests while putting up a 1-2 record straight-up in those games.
• Clemson and its opponents have combined to hit the over two times in those games.
• Clemson’s past three outings have ended with an average of 51.5 points scored. That’s 3.0 fewer points than this contest’s over/under.

Boston College Eagles

• Boston College is winless against the spread (0-3) and 1-2 overall over its past three matchups.
• One time in those three games, the final combined score exceeded the set total.
• The past three Boston College games averaged 2.8 fewer points (51.7) than this matchup’s over/under.

Clemson vs. Boston College key players

Clemson Tigers

• Cade Klubnik leads Clemson with 1,250 yards (250.0 ypg) on 111-of-172 passing with 10 touchdowns and four interceptions this season. He also has 56 rushing yards on 38 carries while scoring one touchdown on the ground.
• Adam Randall has compiled 368 rushing yards on 65 carries, scoring three touchdowns. He’s also added 154 yards (38.5 per game) on 17 catches with three touchdowns.
• Bryant Wesco Jr.’s leads his squad with 431 yards as a receiver. He’s racked up that yardage on 26 receptions (out of 36 targets) and scored five touchdowns.
• T.J. Moore has put together a 272-yard season so far with one touchdown, hauling in 20 passes on 39 targets.
• T.J. Parker has racked up 2.0 sacks to lead the team, while also picking up 3.0 TFL and 15 tackles.
• Clemson’s leading tackler, Wade Woodaz, has 35 tackles and 2.0 TFL this year.
• Ashton Hampton leads the team with one interception, while also collecting 16 tackles, 1.0 TFL, and one pass defended.

Boston College Eagles

• Dylan Lonergan has compiled 1,277 yards (255.4 ypg) while completing 67.4% of his passes and tossing nine touchdown passes with three interceptions this season.
• Turbo Richard has run the ball 64 times for 331 yards, with four touchdowns. He’s also tacked on 17 catches for 165 yards and two touchdowns.
• Jordan McDonald has racked up 81 yards (on 22 carries) with one touchdown.
• Lewis Bond has totaled 38 receptions this season and his team-high yardage total sits at 366 (73.2 yards per game). He’s been targeted 52 times.
• Reed Harris has racked up 285 receiving yards (57.0 yards per game) and two touchdowns on 17 receptions.
• Jeremiah Franklin’s 22 receptions (on 34 targets) have netted him 224 yards (44.8 ypg) and one touchdown.
• Sedarius McConnell has collected 2.0 sacks to lead the team, while also recording 2.0 TFL and seven tackles.
• KP Price is the team’s tackle leader this year. He’s amassed 21 tackles.
• Omar Thornton leads the team with one interception, while also recording 20 tackles, 3.0 TFL, one sack, and one pass defended.