College Football Week 2 Best Games

Data Skrive
Data Skrive

The college football schedule in Week 2, which includes the Fresno State Bulldogs squaring off against the Oregon State Beavers, is not one to miss.

Searching for an edge in college football? We break down the betting odds for all the important matchups below.

Keep reading to check out our previews for this season, and uncover all of our predictions here, too!

Week 2’s Closest Projected College Football Games (by Spread)

Fresno State (2-1) at Oregon State (0-2)

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  • Game Time: 3:30 p.m. ET | Saturday, September 6, 2025
  • Oregon St Last Game: 36-27 L vs Fresno State
  • Fresno State Last Game: 36-27 W vs Oregon State
Odds to Cover

Oregon State -1.5 vs. Fresno State

Bet $20, Payout $38.35

San Diego State (1-0) at Washington State (1-0)

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  • Game Time: 10:15 p.m. ET | Saturday, September 6, 2025
  • Wazzu Last Game: 13-10 W vs Idaho
  • SDSU Last Game: 42-0 W vs Stony Brook
Betting Odds

Washington State -1.5 vs. San Diego State

Bet $20, Payout $38.18

UCLA (0-1) at UNLV (2-0)

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  • Game Time: 8 p.m. ET | Saturday, September 6, 2025
  • UNLV Last Game: 38-21 W vs Sam Houston
  • UCLA Last Game: 43-10 L vs Utah
Odds to Cover

UCLA -2 vs. UNLV

Bet $20, Payout $38.18

Virginia (1-1) at North Carolina State (2-0)

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  • Game Time: 12 p.m. ET | Saturday, September 6, 2025
  • NC State Last Game: 35-31 W vs Virginia
  • Virginia Last Game: 35-31 L vs North Carolina State
Spread

North Carolina State -2.5 vs. Virginia

Bet $20, Payout $36.26

No. 11 Illinois (2-0) at Duke (1-1)

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  • Game Time: 12 p.m. ET | Saturday, September 6, 2025
  • Duke Last Game: 45-19 L vs Illinois
  • Illinois Last Game: 45-19 W vs Duke
Betting Odds

Illinois -2.5 vs. Duke

Bet $20, Payout $38.02

Vanderbilt (1-0) at Virginia Tech (0-1)

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  • Game Time: 7:30 p.m. ET | Saturday, September 6, 2025
  • Virginia Tech Last Game: 24-11 L vs South Carolina
  • Vandy Last Game: 45-3 W vs Charleston Southern
Betting Odds

Virginia Tech -2.5 vs. Vanderbilt

Bet $20, Payout $38.52

Iowa (1-1) at No. 16 Iowa State (3-0)

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  • Game Time: 12 p.m. ET | Saturday, September 6, 2025
  • Iowa St Last Game: 16-13 W vs Iowa
  • Iowa Last Game: 16-13 L vs Iowa State
To Cover the Spread

Iowa State -3 vs. Iowa

Bet $20, Payout $37.39

Baylor (1-1) at No. 17 SMU (1-1)

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  • Game Time: 12 p.m. ET | Saturday, September 6, 2025
  • SMU Last Game: 48-45 L vs Baylor
  • Baylor Last Game: 48-45 W vs SMU
To Cover the Spread

SMU -3 vs. Baylor

Bet $20, Payout $39.42

West Virginia (1-1) at Ohio (1-1)

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  • Game Time: 4 p.m. ET | Saturday, September 6, 2025
  • Ohio Last Game: 17-10 W vs West Virginia
  • WVU Last Game: 17-10 L vs Ohio
Betting Odds

West Virginia -3.5 vs. Ohio

Bet $20, Payout $38.02

Boston College (1-0) at Michigan State (1-0)

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  • Game Time: 7:30 p.m. ET | Saturday, September 6, 2025
  • Mich. State Last Game: 23-6 W vs Western Michigan
  • BC Last Game: 66-10 W vs Fordham
To Cover the Spread

Michigan State -3.5 vs. Boston College

Bet $20, Payout $38.18
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The BetDecider team brings you the most current sports betting content, with expert insights and tips. Our aim is that you can make an informed betting decision, including best odds and exclusive sportsbook offers, to maximize your betting experience.

Ryan Knuppel

Knup Solutions [molongui_author_name]

About Ryan Knuppel

Ryan has been one of the leading sports business & iGaming professionals for over 15 years. He started as a freelance writer and now operates one of the top sports content agencies around, Knup Solutions. He has literally written 10,000 plus sports and betting related articles across the web.

 

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Betting Guide

How Money Line Works?

Moneyline betting is by far the easiest way to place a sports wager. There are no point spreads to parse, no garbage-time free throws to ruin your betting day, and no last-minute meaningless touchdowns to take you from a winner to a loser.

How to Bet Odds

When we, as sports fans, learned our multiplication tables, we aced the number 7. Seven, 14, 21, 28, 35, 42 were easy because we all watched football on the weekends. Multiplication by sevens, then add a three, a six after a missed PAT.

How to Bet on NFL Games

Baseball is America’s pastime, but football is America’s crazed passion, with its weekly schedule of games, millions of television viewers across the country and the world, and the billion-dollar stadiums that serve as Sunday cathedrals in 32 American cities.

What is the Spread?

If you are a golfer or have ever played on a bowling team, think of a point spread like a handicap. It is a way for two teams of differing abilities to play each other on equal footing.  The better team, and the favorite in the game, gives a certain amount …