The No. 6 Iowa State Cyclones (23-3, 10-3 Big 12) hit the road in Big 12 play against the No. 23 BYU Cougars (19-7, 7-6 Big 12) on Saturday, February 21, 2026 at 10:30 p.m. ET. The Cyclones are 2.5-point favorites in the game. The point total for the matchup is set at 154.5.

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Iowa State vs. BYU betting lines

• Iowa State moneyline odds to win: -164
• BYU moneyline odds to win: +135
• Spread: Iowa State (-2.5)
• Total: 154.5

Iowa State statistics, trends and more

As the away team

• Iowa State has done a better job covering the spread in away games (4-3-0) than it has in home games (8-7-0).
• The Cyclones have eclipsed the over/under in seven of 15 home games (46.7%), compared to two of seven road games (28.6%).
• As a moneyline favorite, Iowa State has won a higher percentage of its games at home (1.000) compared to road games (.500).

Recent trends

• The Cyclones have been scoring 76.7 points per game in their last 10 times on the court, an average that’s significantly lower than the 83.7 they’ve scored over the course of the 2025-26 season.
• Iowa State’s points-allowed average over its last 10 games (67.3) is 2.7 more points per game than the team is allowing over the entire season (64.6).
• While the Cyclones are knocking down more threes per game over their past 10 outings (9.3 per game) in comparison to their season-long average (9.0), they are doing so while shooting a lower percentage (38.3% from beyond the arc over the last 10, 39.8% on the season).

Iowa State betting records this season

• ATS Record: 15-11-0 (Home: 8-7-0; Away: 4-3-0)
• ATS Record When Favored by 2.5+: 14-11-0 (As Favorite: 14-11-0; As Underdog: 1-0-0)
• O-U-P: 12-14-0 (Home: 7-8-0; Away: 2-5-0)
• Record When Moneyline Favorite: 20-3 (Home: 13-0; Away: 3-3)
• Record When Moneyline Underdog: 1-0 (Home: 0-0; Away: 1-0)

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BYU statistics, trends and more

As the home team

• BYU’s winning percentage against the spread at home is .333 (4-8-0). On the road, it is .429 (3-4-0).
• Cougars games have gone above the over/under less frequently at home (six times out of 12) than away (four of seven) this season.
• When moneyline underdogs, the Cougars have won the same percentage of games (.000) at home (0-1) and away (0-3).

Recent trends

• While the Cougars are scoring 85.8 points per game in 2025-26, they have fallen short of that in their previous 10 games, producing 81.8 points per contest.
• While BYU is ceding 74.5 points per game in 2025-26, it has been worse over its previous 10 games, allowing 83.9 points per contest.
• The Cougars are making 8.2 treys per contest in their past 10 games, which is 0.7 fewer three-pointers than their average for the season (8.9). Additionally, they have a worse three-point percentage over their past 10 contests (33.7%) compared to their season average from three-point land (35.7%).

BYU betting records this season

• ATS Record: 11-15-0 (Home: 4-8-0; Away: 3-4-0)
• ATS Record When Underdog by 2.5+: 2-2-0 (As Favorite: 9-11-0; As Underdog: 2-4-0)
• O-U-P: 13-13-0 (Home: 6-6-0; Away: 4-3-0)
• Record When Moneyline Favorite: 18-1 (Home: 9-0; Away: 3-1)
• Record When Moneyline Underdog: 0-5 (Home: 0-1; Away: 0-3)