The Bowling Green Falcons (2-1) visit the Louisville Cardinals (2-0) at L&N Federal Credit Union Stadium on Saturday, September 20, 2025.

The Cardinals are very heavy favorites (currently -26.5) in their game against the Falcons, with the over/under being 51.5 points. (In terms of the moneyline, the Cardinals are -4545 and the Falcons are +1550.)

Keep reading for our betting preview for this this contest between the Cardinals and the Falcons, and discover all of our expert predictions here, too!

Louisville vs. Bowling Green betting lines

• Spread favorite: Cardinals (-26.5)
• Moneyline: Cardinals (-4545), Falcons (+1550)
• Total: 51.5 points
• TV Channel: ACC Network
• Live Stream: Fubo

Louisville vs. Bowling Green betting info and stats

Louisville has not won a game against the spread this season (0-2-0). Louisville has yet to cover the spread when the favorite by at least 26.5 points (a 0-1 ATS record). Louisville has won both games as a moneyline favorite this season. Bowling Green has a pair of wins against the spread this season (2-1-0). Bowling Green has played a game as the underdog on the moneyline in two games this season, and it split the two games.

Louisville vs. Bowling Green key players

Louisville Cardinals

• Miller Moss has 374 passing yards for Louisville, completing 62.5% of his passes and tossing two touchdowns and two interceptions this season.
• Isaac Brown has carried the ball 18 times for a team-high 230 yards on the ground and has found the end zone three times.
• Shaun Boykins has piled up 40 yards on five carries.
• Chris Bell’s 146 yards as a receiver lead the team. He’s been targeted 18 times and has totaled nine receptions and one touchdown.
• Caullin Lacy has put up a 74-yard season so far, reeling in six passes on nine targets.
• Kris Hughes has a total of 50 receiving yards so far this year, grabbing three passes and scoring one touchdown.
• Clev Lubin paces the team with 3.5 sacks. He’s also the team’s tackle leader, and has collected 2.0 TFL and 14 tackles.
• Jabari Mack has picked off a team-high one pass. He also has one pass defended to his name.

Bowling Green Falcons

• Drew Pyne has compiled 529 yards on 67.1% passing while tossing two touchdown passes with zero interceptions this season.
• Kaderris Roberts has rushed for 152 yards on 27 carries so far this year. He’s also tacked on 10 catches, totaling 55 yards.
• Cameron Pettaway has totaled 124 yards on 26 carries.
• Jyrin Johnson has registered 10 receptions this season and his team-high yardage total sits at 138 (46.0 yards per game). He’s been targeted 14 times and has one touchdown.
• Finn Hogan has caught eight passes and compiled 114 receiving yards (38.0 per game).
• RJ Garcia II’s 10 receptions (on 13 targets) have netted him 105 yards (35.0 ypg).
• Eriq George has 2.0 sacks to lead the team, and also has 2.0 TFL and three tackles.
• Dorian Pringle has 17 tackles, 3.0 TFL, 0.5 sacks, and one interception, and leads the team in both tackles and interceptions.