The Louisville Cardinals and the Toledo Rockets meet for the Boca Raton Bowl on December 23, 2025.

The Cardinals are solid favorites (-9.5) in their game versus the Rockets, with the over/under being 43.5 points. (In terms of the moneyline, the Cardinals are -412 and the Rockets are +317.)

Keep reading for our betting primer for this this contest between the Cardinals and the Rockets, and uncover all of our predictions here, too!

Louisville vs. Toledo betting lines

• Spread favorite: Cardinals (-9.5)
• Moneyline: Cardinals (-412), Rockets (+317)
• Total: 43.5 points
• TV Channel: ESPN
• Live Stream: Fubo

Louisville vs. Toledo betting info and stats

Louisville is 4-8-0 against the spread so far this season. Louisville has covered the spread in one game when the favorite by at least 9.5 points (a 1-5 ATS record). Louisville has been the moneyline favorite 10 times this season, and sports a 7-3 record in those games. Toledo has an against-the-spread record of 9-3-0 this season. When Toledo is an underdog of 9.5 points or more, it has always covered the spread (1-0 ATS). Toledo has been an underdog on the moneyline in one game this season, and failed to pick up the victory.

Louisville vs. Toledo recent stats and trends

Louisville Cardinals

• Louisville has covered the spread once in its past three matchups while putting together a 1-2 record straight-up in those games.
• Louisville and its opponents did not combine to hit the over in any of those games.
• The last three Louisville games averaged 49.2 total points, 5.7 more points than this matchup’s over/under.

Toledo Rockets

• Toledo has covered the spread in each of its past three contests while putting up a 1-2 record straight-up in those games.
• The final combined score of the last three Toledo games exceeded the set total once.
• Toledo’s last three games have ended with an average of 45.5 points scored. That’s 2.0 more points than this contest’s over/under.

Louisville vs. Toledo key players

Louisville Cardinals

• Miller Moss has recorded 2,526 yards (229.6 ypg) on 228-of-356 passing with 14 touchdowns compared to seven interceptions this season.
• Isaac Brown has racked up 782 yards on 91 carries while finding paydirt five times as a runner.
• This season, Keyjuan Brown has carried the ball 81 times for 592 yards (65.8 per game) and six touchdowns.
• Chris Bell has hauled in 72 receptions for 917 yards (83.4 yards per game) to lead the team so far this season. He’s found the end zone six times as a receiver.
• Caullin Lacy has hauled in 54 receptions totaling 547 yards, finding the end zone two times as a receiver so far this campaign.
• Dacari Collins has compiled 13 catches for 219 yards, an average of 21.9 yards per game. He’s scored one time as a receiver this season.
• Clev Lubin has racked up 6.5 sacks to pace the team, while also picking up 6.0 TFL and 40 tackles.
• TJ Quinn, Louisville’s tackle leader, has 73 tackles, 5.0 TFL, three sacks, and two interceptions this year.
• Antonio Watts has a team-high three interceptions to go along with 37 tackles, 5.0 TFL, 2.5 sacks, and three passes defended.

Toledo Rockets

• Tucker Gleason has 2,515 passing yards, or 209.6 per game, so far this season. He has completed 64.7% of his passes and has collected 21 touchdowns with nine interceptions. He’s also helped out on the ground with 13.1 rushing yards per game while scoring as a runner four times.
• DeaMonte Trayanum is his team’s leading rusher with 166 carries for 950 yards, or 95.0 per game. He’s found paydirt 11 times on the ground, as well. Trayanum has also chipped in with 19 catches for 207 yards and two receiving touchdowns.
• Kenji Christian has piled up 99 carries and totaled 501 yards with four touchdowns while also gaining 181 yards through the air with one touchdown.
• Junior Vandeross III has hauled in 947 receiving yards on 75 catches to pace his squad so far this season while scoring 11 touchdowns as a receiver.
• Trayvon Rudolph has collected 423 receiving yards (35.3 yards per game) and two touchdowns on 38 receptions.
• Jacob Petersen has racked up 275 reciving yards (22.9 ypg) and two touchdowns this season.
• Malachi Davis paces the team with 5.5 sacks, and also has 8.0 TFL and 28 tackles.
• K’Von Sherman, Toledo’s leading tackler, has 66 tackles, 13.0 TFL, and 4.5 sacks this year.
• Braden Awls has picked off a team-leading five passes. He also has 43 tackles, 4.0 TFL, 0.5 sacks, and five passes defended to his name.