The Oregon Ducks (11-1) host the James Madison Dukes (12-1) at Autzen Stadium in Eugene, Oregon in the first round of the College Football Playoff. Kickoff is at 7:30 p.m. ET, and Oregon is a 20.5 favorite.

The Ducks are very big favorites (currently -20.5) in their game versus the Dukes, with the over/under being 45.5 points. (On the moneyline, the Ducks are -1818 and the Dukes are +980.)

Below you’ll find our betting primer for this this game between the Ducks and the Dukes, and discover all of our predictions here, too!

Oregon vs. James Madison betting lines

• Spread favorite: Ducks (-20.5)
• Moneyline: Ducks (-1818), Dukes (+980)
• Total: 45.5 points

Oregon vs. James Madison betting info and stats

Oregon has won seven games against the spread this season (7-5-0). Oregon is 3-3 ATS when the favorite by at least 20.5 points. In the 10 games as the moneyline favorite, Oregon has put up a 9-1 record. James Madison has won eight games against the spread so far this season (8-5-0). James Madison has played a game as an underdog on the moneyline in one game this season, and failed to pick up the victory.

Oregon vs. James Madison recent stats and trends

Oregon Ducks

• Oregon is a perfect 3-0 against the spread in its past three games, and has a 3-0 straight-up record in those contests.
• Oregon and its opponents have combined to hit the over in two of those games.
• The past three Oregon games averaged 6.7 more points (52.2) than this matchup’s over/under.

James Madison Dukes

• James Madison is 2-1 against the spread over its past three games and has a 3-0 straight-up record in those matchups.
• The final combined score of the past three James Madison games has exceeded the set total two times.
• The past three James Madison games averaged 5.3 more points (50.8) than this matchup’s over/under.

Oregon vs. James Madison key players

Oregon Ducks

• Dante Moore has recorded 2,733 yards (227.8 ypg) on 227-of-313 passing with 24 touchdowns compared to six interceptions this season. In addition, he’s added 191 rushing yards (15.9 ypg) on 57 carries while scoring one touchdown on the ground.
• Noah Whittington has racked up 774 yards on 112 carries while finding the end zone six times.
• Jordon Davison has carried the ball 87 times for 535 yards (44.6 per game) and 13 touchdowns.
• Malik Benson’s leads his squad with 526 yards as a receiver. He’s racked up that yardage on 31 catches (out of 47 targets) and scored four touchdowns.
• Kenyon Sadiq has caught 40 passes for 490 yards (44.5 yards per game) and eight touchdowns this year.
• Dakorien Moore has hauled in 28 receptions for 443 yards, an average of 55.4 yards per game. He’s scored three times as a receiver this season.
• Teitum Tuioti has racked up 7.0 sacks to pace the team, while also picking up 8.0 TFL and 49 tackles.
• Oregon’s top-tackler, Bryce Boettcher, has 72 tackles, 1.0 TFL, one sack, and one interception this year.
• Dillon Thieneman has a team-high two interceptions to go along with 49 tackles, 1.0 TFL, one sack, and two passes defended.

James Madison Dukes

• Alonza Barnett III has thrown for 2,533 yards (194.8 ypg) to lead James Madison, completing 59.9% of his passes and tossing 21 touchdown passes and eight interceptions this season. He is also a playmaker on the ground, racking up 544 yards (41.8 ypg) on 115 carries with 14 touchdowns.
• The team’s top rusher, Wayne Knight, has carried the ball 190 times for 1,263 yards (97.2 per game), with nine touchdowns this year. He’s proven to be a dual threat, hauling in 379 receiving yards (29.2 per game) on 37 catches with one receiving touchdown.
• Landon Ellis has registered 33 receptions this season and his team-high yardage total sits at 541 (49.2 yards per game). He’s been targeted 51 times and has five touchdowns.
• Nick DeGennaro has caught 23 passes and compiled 410 receiving yards (31.5 per game) with four touchdowns.
• Sahir West leads the team with 6.5 sacks, and also has 8.0 TFL and 27 tackles.
• Trent Hendrick, James Madison’s tackle leader, has 44 tackles, 4.0 TFL, and three sacks this year.
• Justin Eaglin leads the team with four interceptions, while also collecting 13 tackles and four passes defended.