The No. 7 Ole Miss Rebels (7-1) meet a conference opponent when they host the South Carolina Gamecocks (3-5) on Saturday, November 1, 2025 at Vaught-Hemingway Stadium in an SEC showdown.

The Rebels are expected to win by at least two scores (currently -12.5) against the Gamecocks. The over/under for this game is 55.5 points.

Below you can find our betting preview for this this game between the Rebels and the Gamecocks, and uncover all of our expert predictions here, too!

Ole Miss vs. South Carolina betting lines

• Spread favorite: Rebels (-12.5)
• Moneyline: Rebels (-483), Gamecocks (+367)
• Total: 55.5 points
• TV Channel: ESPN
• Live Stream: Fubo

Ole Miss vs. South Carolina betting info and stats

Ole Miss is 5-3-0 against the spread so far this season. Ole Miss has covered the spread two times this season when listed as a favorite by at least 12.5 points. In six games as the moneyline favorite, Ole Miss has not lost (6-0). South Carolina has an against-the-spread record of 4-4-0 so far this season. This is the fifth time this year South Carolina is the moneyline underdog, and have lost every such contest.

Ole Miss vs. South Carolina recent stats and trends

Ole Miss Rebels

• Ole Miss is 1-2 against the spread and 2-1 overall in its last three games.
• In two of those three games, the final combined score has exceeded the set total.
• Ole Miss’ past three outings have ended with an average of 55.8 points scored. That’s 0.3 more points than this contest’s over/under.

South Carolina Gamecocks

• South Carolina is 1-2 against the spread and 2-1 overall over its last three contests.
• In one of those three games, the final combined score exceeded the set total.
• The past three South Carolina games averaged 10.7 fewer points (44.8) than this matchup’s over/under.

Ole Miss vs. South Carolina key players

Ole Miss Rebels

• Trinidad Chambliss has thrown for 1,864 yards, completing 61% of his passes and tossing nine touchdowns and one interception this season. He’s also run for 376 yards (47.0 ypg) on 82 carries with five rushing touchdowns.
• Kewan Lacy has racked up 696 yards on 165 carries while finding the end zone 12 times. He’s also caught 18 passes for 114 yards (16.3 per game).
• Harrison Wallace III’s team-high 464 yards as a receiver have come on 26 receptions (out of 51 targets) with two touchdowns.
• Dae’Quan Wright has hauled in 22 receptions totaling 404 yards, finding the end zone three times as a receiver so far this campaign.
• Deuce Alexander’s 25 receptions have yielded 394 yards and one touchdown.
• Princewill Umanmielen has collected 3.5 sacks to lead the team, while also picking up 4.0 TFL and 21 tackles.
• T.J. Dudley is the team’s tackle leader this year. He’s picked up 47 tackles and 1.0 TFL.
• Cedrick Beavers leads the team with one interception, while also recording 1.0 TFL and one pass defended.

South Carolina Gamecocks

• LaNorris Sellers has thrown for 1,356 yards on 108-of-171 passing with six touchdowns and three interceptions this season. He has chipped on the ground, as well, with 175 yards and two rushing touchdowns.
• Rahsul Faison is his team’s leading rusher with 69 carries for 298 yards, or 37.3 per game. He’s found the end zone three times on the ground, as well.
• Vandrevius Jacobs has hauled in 343 receiving yards on 21 receptions to pace his squad so far this season while scoring two touchdowns as a receiver.
• Nyck Harbor has recorded 332 receiving yards (41.5 yards per game) and three touchdowns on 18 receptions.
• Brady Hunt’s 16 grabs (on 23 targets) have netted him 144 yards (20.6 ypg).
• Bryan Thomas Jr. has collected 5.0 sacks to lead the team, while also recording 6.0 TFL and 23 tackles.
• DQ Smith is the team’s tackle leader this year. He’s amassed 40 tackles and one interception.
• Peyton Williams has picked off a team-leading two passes. He also has 32 tackles and two passes defended to his name.