Cardinals vs. Tigers Betting Lines, Odds, & Player Matchups May 21, 2025

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Data Skrive

The St. Louis Cardinals (27-22) host the Detroit Tigers (32-17) on Wednesday at Busch Stadium, beginning at 1:15 p.m. ET. The Cardinals are favored on the moneyline (-114), while the Tigers are -105 underdogs. The Tigers are spread favorites (1.5) with +158 odds, despite being the moneyline underdog. Andre Pallante starts for St. Louis, and Brant Hurter is Detroit’s choice to start.

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Odds to Win

Cardinals to win vs Tigers -114

Bet $20, Payout $37.54

Cardinals vs. Tigers betting lines

  • Favorite: Cardinals (-114)
  • Underdog: Tigers (-105)
  • Over/under: 8.5

Cardinals betting info, hitting leaders, & pitching

Cardinals betting info

  • The Cardinals have been the moneyline favorite 16 total times this season. They’ve finished 9-7 in those games.
  • St. Louis has gone 7-5 (winning 58.3% of its games) when playing as moneyline favorites of -114 or shorter.
  • Based on this game’s moneyline, the Cardinals’ implied win probability is 53.3%.
  • St. Louis has had an over/under set by bookmakers 49 times, and have combined with opponents to go over the total in 26 of those games (26-21-2).
  • The Cardinals are 29-20-0 ATS this season.

Cardinals hitting info

  • Lars Nootbaar has hit a team-high seven home runs.
  • Among hitters in MLB play, Nootbaar ranks 63rd in homers and 58th in RBI.
  • Brendan Donovan is batting .330 to pace his team.
  • Donovan currently ranks 177th in homers and 85th in RBI in the bigs.
  • Nolan Arenado is batting .247 with 10 doubles, five home runs and 17 walks.
  • Willson Contreras has totaled 27 runs batted in to pace his team.
  • Contreras has safely hit in two straight games. During his last five outings he is batting .190 with two doubles and two RBIs.

Cardinals pitching rankings

  • The Cardinals pitching staff ranks 29th in the majors with a collective 7.2 strikeouts per nine innings.
  • St. Louis has the 11th-ranked team ERA among all MLB pitching staffs (3.71).
  • Pitchers for the Cardinals combine for the No. 9-ranked WHIP in the majors (1.211).
  • Cardinals pitchers combine to allow the second-fewest home runs in baseball (37 total, 0.8 per game).
  • St. Louis fell to the Tigers 5-4 in its last game with five strikeouts while allowing seven hits.

Tigers betting info, hitting leaders, & pitching

Tigers betting info

  • This season, the Tigers have been the underdog 20 times and won 10, or 50%, of those games.
  • This season, Detroit has won 10 of its 20 games, or 50%, when it’s the underdog by at least -105 on the moneyline.
  • The moneyline for this contest implies a 51.2% chance of a victory for the Tigers.
  • Detroit’s games have gone over the total in 25 of its 49 chances.
  • The Tigers are 27-22-0 against the spread this season.

Tigers hitting info

  • Spencer Torkelson leads Detroit in home runs with 12 and runs batted in with 38.
  • Among all hitters in the majors, Torkelson’s home run total is eighth, and his RBI total is sixth.
  • Riley Greene’s 12 home runs are most among Detroit batters. He’s driven in 34 runs this season while slugging .535.
  • Among all major league hitters, Greene is eighth in home runs and 13th in RBI.
  • Greene has hit safely in three straight games. In his last five games he is batting .400 with three doubles, two home runs, a walk and seven RBIs.
  • Gleyber Torres is slashing .283/.365/.435 this season for the Tigers.
  • Kerry Carpenter has collected 47 hits this season and has an OBP of .310. He’s slugging .512 on the year.

Tigers pitching rankings

  • The Tigers have an 8.8 K/9 this season as a pitching staff, ninth-best in baseball.
  • Detroit pitchers have a combined ERA of 3.38 ERA this year, sixth-best in baseball.
  • The Tigers have a combined WHIP of just 1.186 as a pitching staff, which is the eighth-best in baseball this season.
  • With 53 homers allowed, the Tigers rank 16th in the league at preventing long balls.
  • Last time out, Detroit defeated the Cardinals, 5-4, with 10 strikeouts and eight hits allowed.
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Betting Guide

How Money Line Works?

Moneyline betting is by far the easiest way to place a sports wager. There are no point spreads to parse, no garbage-time free throws to ruin your betting day, and no last-minute meaningless touchdowns to take you from a winner to a loser.

How to Bet Odds

When we, as sports fans, learned our multiplication tables, we aced the number 7. Seven, 14, 21, 28, 35, 42 were easy because we all watched football on the weekends. Multiplication by sevens, then add a three, a six after a missed PAT.

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Baseball is America’s pastime, but football is America’s crazed passion, with its weekly schedule of games, millions of television viewers across the country and the world, and the billion-dollar stadiums that serve as Sunday cathedrals in 32 American cities.

What is the Spread?

If you are a golfer or have ever played on a bowling team, think of a point spread like a handicap. It is a way for two teams of differing abilities to play each other on equal footing.  The better team, and the favorite in the game, gives a certain amount …