Blue Jays vs. Padres Betting Lines, Odds, & Player Matchups May 21, 2025

Data Skrive
Data Skrive

The San Diego Padres (27-19) will aim to break a four-game losing streak when they visit the Toronto Blue Jays (23-24) on Wednesday at 7:07 p.m. ET. The Padres (+129) are not expected to end the streak against the Blue Jays (-153). Toronto has Kevin Gausman set to start, and San Diego will counter with Randy Vasquez.

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Betting Odds

Blue Jays to win vs Padres -153

Bet $20, Payout $33.07

Blue Jays vs. Padres betting lines

  • Favorite: Blue Jays (-153)
  • Underdog: Padres (+129)
  • Over/under: 8.5

Blue Jays betting info, hitting leaders, & pitching

Blue Jays betting info

  • The Blue Jays have been favored on the moneyline 17 total times this season. They’ve finished 8-9 in those games.
  • Toronto has gone 4-2 (winning 66.7% of its games) when playing as moneyline favorites of -153 or shorter.
  • The Blue Jays have an implied moneyline win probability of 60.5% in this game.
  • Toronto has had an over/under set by bookmakers 46 times, and have combined with opponents to go over the total in 22 of those games (22-22-2).
  • The Blue Jays have covered 63% of their games this season, going 29-17-0 ATS.

Blue Jays hitting info

  • Vladimir Guerrero Jr. paces the Blue Jays with six home runs while accumulating a team-high batting average of .289.
  • Among all batters in MLB action, Guerrero’s home run total ranks 81st and his RBI tally ranks 96th.
  • Guerrero enters this game on a two-game hitting streak. In his last five games he is batting .267 with two home runs, five walks and two RBIs.
  • Bo Bichette’s 22 runs batted in pace his team.
  • Bichette currently ranks 145th in home runs and 85th in RBI in the majors.
  • George Springer is batting .257 with 10 doubles, a triple, five home runs and 25 walks.
  • Alejandro Kirk is hitting .283 with four doubles, three home runs and five walks.

Blue Jays pitching rankings

  • The pitching staff for the Blue Jays has a collective 9.3 K/9, the fourth-best in the majors.
  • Toronto has the 23rd-ranked team ERA among all MLB pitching staffs (4.23).
  • The Blue Jays average MLB’s 13th-ranked WHIP (1.237).
  • The Blue Jays give up the second-most home runs in baseball (68 total, 1.4 per game).
  • In its 3-0 win last time out, Toronto struck out eight Padres batters while allowing five hits.

Padres betting info, hitting leaders, & pitching

Padres betting info

  • The Padres have entered the game as underdogs 19 times this season and won 10, or 52.6%, of those games.
  • San Diego has a record of 1-4 when it’s set as an underdog of +129 or more by oddsmakers this season.
  • The oddsmakers’ moneyline implies a 43.7% chance of a victory for the Padres.
  • San Diego and its opponents have gone over the total this season in 19 of its 46 opportunities.
  • The Padres are 26-20-0 ATS in their 46 games with a spread this season.

Padres hitting info

  • Fernando Tatis Jr. leads San Diego in home runs (12) and runs batted in (27) this season while batting .303.
  • In all of Major League Baseball, Tatis ranks eighth in home runs and 40th in RBI.
  • Tatis has safely hit in four games in a row. In his last five games he is batting .200 with a double, a home run, a walk and an RBI.
  • Manny Machado is batting .310 to lead San Diego, while adding three homers and 20 runs batted in this season.
  • Machado is 177th among hitters in the big leagues in home runs, and 105th in RBI.
  • Luis Arraez has collected 48 base hits, an OBP of .333 and a slugging percentage of .414 this season.
  • Arraez has hit safely in seven straight games. In his last 10 outings he is batting .341 with two doubles, a triple, a walk and three RBIs.
  • Xander Bogaerts has collected 39 hits this season and has an OBP of .335. He’s slugging .361 on the year.

Padres pitching rankings

  • The Padres average nine strikeouts per nine innings as a pitching staff, seventh-most in the big leagues.
  • San Diego has pitched to a 3.42 ERA this season, which ranks eighth in baseball.
  • The Padres have a combined 1.165 WHIP as a pitching staff, fifth-lowest in MLB.
  • The Padres have given up the 11th-fewest long balls so far this season with 48 home runs allowed.
  • San Diego pitchers struck out seven Blue Jays hitters while allowing three base hits in a 3-0 loss its last time out.
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