Vanderbilt vs. Nebraska betting: March Madness Second Round preview for March 21

Data Skrive

The No. 5 seed from the South Region bracket, the Vanderbilt Commodores (27-8), face the No. 4 seed Nebraska Cornhuskers (27-6) on Saturday with a spot in the Sweet 16 of the NCAA Tournament on the line. Vanderbilt has been installed as a 2.5-point favorite to win this second round matchup, which begins at 8:55 p.m. ET on TNT. The matchup has an over/under set at 146.5 points.

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Spread

Vanderbilt Cover -2.5 vs Nebraska -107

Bet $20, Payout $38.69

Vanderbilt vs. Nebraska betting lines

  • Vanderbilt moneyline odds to win: -138
  • Nebraska moneyline odds to win: +114
  • Spread: Vanderbilt (-2.5)
  • Total: 146.5

Vanderbilt statistics, trends and more

Recent trends

  • On offense, the Commodores have struggled over their last 10 games, scoring 80.4 points per contest over that stretch as opposed to the 86.1 they’ve racked up over the course of this year.
  • Vanderbilt has been less stingy on the defensive side of the ball lately, allowing 78.5 points per game over its last 10 outings compared to the 75 points per game its opponents are averaging over the 2025-26 season.
  • During their last 10 contests, the Commodores are making 1.2 fewer three-pointers per game than their season long average (8.3 compared to 9.5 season-long), while also shooting a lower percentage from beyond the arc in that span (34.6% compared to 35.6% season-long).

Vanderbilt betting records this season

  • ATS Record: 18-17-0 (Home: 8-8-0; Away: 6-6-0)
  • ATS Record When Favored by 2.5+: 14-14-0 (As Favorite: 14-14-0; As Underdog: 4-3-0)
  • O-U-P: 16-19-0 (Home: 8-8-0; Away: 6-6-0)
  • Record When Moneyline Favorite: 22-5 (Home: 12-2; Away: 6-2)
  • Record When Moneyline Underdog: 4-3 (Home: 0-1; Away: 2-2)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
47.6 (42nd in nation) 42.5 (74th) 32.3 (155th) 31.3 (203rd) 16.3 (46th) 8.9 (19th)

Need to know more about sports betting before you put down a wager on Vanderbilt vs. Nebraska? Here’s everything you need to know about how to bet.

Nebraska statistics, trends and more

Recent trends

  • The Cornhuskers are scoring 71 points per game in their past 10 games, which is 6.2 fewer points than their average for the season (77.2).
  • Nebraska is surrendering 64.6 points per game in its previous 10 games, which is one fewer point than it is allowing for the season (65.6).
  • Over their last 10 games, the Cornhuskers are sinking 9.9 three-pointers per game, 0.7 fewer threes than their season average (10.6). They also own a worse three-point percentage over their last 10 games (34.3%) compared to their season average (35.3%).

Nebraska betting records this season

  • ATS Record: 18-15-0 (Home: 8-10-0; Away: 7-3-0)
  • ATS Record When Underdog by 2.5+: 4-1-0 (As Favorite: 14-13-0; As Underdog: 4-2-0)
  • O-U-P: 11-22-0 (Home: 4-14-0; Away: 4-6-0)
  • Record When Moneyline Favorite: 22-3 (Home: 14-2; Away: 4-1)
  • Record When Moneyline Underdog: 3-3 (Home: 0-0; Away: 3-2)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
46.4 (101st in nation) 40.1 (18th) 32.6 (138th) 31.5 (216th) 18 (12th) 9.3 (35th)
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About Ryan Knuppel

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